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Treating with copper is treating with a fish poison. The trick is to maintain its concentration low enough so the fish don't die and yet high enough to kill the target microbe/parasite. This control has to be by the aquarist taking regular copper concentration readings. The test kit has to be the one recommended by the medication manufacturer AND the manufacturer has to tell you what the concentration range is, according to that test kit.
A fish in copper treatment often stops eating. Copper is a stressful treatment. That is one reason I don't like the use of CopperSafe. The manufacturer (Mardel) suggests it be used for a full month. No way!![]()
I prefer hyposalinity for Marine Ich (Cryptocaryon irritans) treatment. But when I have to use a copper, I use and prefer Cupramine. Safer and gentler and useful in even half the recommended concentration. With Cupramine you only have to use it for 14 days.
I think that the copper is affecting your fishes, like you think. I would recommend stopping the copper treatment by doing the following: Perform a large water change (can you do a 70% or more water change?). After the change, start up some fresh carbon, a Poly Filter, or copper absorbing material (or all the above!).
Most likely the Marine Ich has be eradicated. But unless you've been monitoring the copper level, there is no sure way of telling right now. Time will tell. While you're holding and watching the fish for confirmation they are cured, I would obtain some Cupramine (by Seachem) and their copper test kit to have on hand in case you have to treat the fish again.
While your fish are recoverying, make sure they are getting the right foods with the correct supplements. See:
Feeding Marine Fish and Fish Nutrition
You should also be adding Beta Glucan to their diet while they are recoverying. Beta Glucan is found in (human) health food stores.
Good luck! We're here to help!![]()



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