Unfortunately, an evaluation of what might have happened is hard to do. And then, after the investigation, you still might be left with an unknown. On the other hand an investigation could turn up some possibilities.
What you describe could be injury or infection. There is no way from what you've provided so far on which would be more likely. If you really want to investigate the possibilities it requires a lot of information from. The investigation is only as good as the quality and details of the information you provide.
Here is the starting information you need to provide:
How old is your tank? When did it originally cycle?
What is the size (dimensions and gallonage) of your aquarium? Does the gallonage include the volume from the sump and any refugium?
Do you use carbon, skimmer, mechanical or other chemical filtration? List all along with their maintenance.
Do you have live rock in the system? How many pounds or amount and where is it put?
Other than live rock hitchhikers, list all marine life & sizes in the tank (fish, inverts, corals, clams, snails, crabs, shrimp, etc.).
Do you use a quarantine tank and procedure?
Foods you use and feeding schedules.
What is the scientific name of this fish? What was it's size/length.
How long have you had this fish? If the fish was recently acquired (6 weeks or less), two more questions: Did you treat it or give it a dip before it went into the aquarium? How did you acclimate it – what procedure?
Do you use any vitamins? Fat additives? Any elemental or other additives? Please list all.
Chemistries – Do you test for Phosphate, alkalinity, calcium and magnesium? Please give actual current numbers for everything. I would like test kit test results, not dip stick results and actual numbers even if you think all is fine/okay. Have these numbers been changing lately?
Water parameters – please give actual numbers (pH and your pH range, salinity or sp. gr. & range, temperature range)
Do you see any of the following in your system: hair algae; micro algae; cyanobacteria growths (red slime algae); dinoflagellate (zooxanthellae) growths; brown algae; diatom growth; slimes; off-colored patches on rock or substrate that are not coralline; etc.?
Water changes (how much and how often).
What is your source water? (Tap water, RO water, DI water, RO/DI, distilled, etc.)
List what you added or taken out of your aquarium system (living, decorations, and equipment) during the past 6 weeks.
Maintenance schedule. What have you done lately?



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